D Neil Wedlock Selected Research

Bovine Tuberculosis

12/2020	Self-assembled particulate vaccine elicits strong immune responses and reduces Mycobacterium avium subsp. paratuberculosis infection in mice.
1/2016	Display of Antigens on Polyester Inclusions Lowers the Antigen Concentration Required for a Bovine Tuberculosis Skin Test.
4/2014	New skin test for detection of bovine tuberculosis on the basis of antigen-displaying polyester inclusions produced by recombinant Escherichia coli.
3/2014	Novel particulate vaccines utilizing polyester nanoparticles (bio-beads) for protection against Mycobacterium bovis infection - a review.
10/2013	Subcutaneous administration of a 10-fold-lower dose of a commercial human tuberculosis vaccine, Mycobacterium bovis bacillus Calmette-Guerin Danish, induced levels of protection against bovine tuberculosis and responses in the tuberculin intradermal test similar to those induced by a standard cattle dose.
12/2011	Protection against bovine tuberculosis induced by oral vaccination of cattle with Mycobacterium bovis BCG is not enhanced by co-administration of mycobacterial protein vaccines.
7/2011	Update on vaccination of cattle and wildlife populations against tuberculosis.
5/2008	Enhanced protection against bovine tuberculosis after coadministration of Mycobacterium bovis BCG with a Mycobacterial protein vaccine-adjuvant combination but not after coadministration of adjuvant alone.
11/2007	Enhancement of the sensitivity of the whole-blood gamma interferon assay for diagnosis of Mycobacterium bovis infections in cattle.
10/2005	Identification of immune response correlates for protection against bovine tuberculosis.

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D Neil Wedlock Research Topics

Disease

15	Bovine Tuberculosis 12/2020 - 05/2003
13	Tuberculosis (Tuberculoses) 12/2016 - 09/2003
12	Infections 01/2021 - 05/2003
3	Communicable Diseases (Infectious Diseases) 11/2018 - 01/2017
3	Mastitis 07/2014 - 08/2008
2	Paratuberculosis (Johne's Disease) 11/2018 - 09/2011
2	Necrosis 11/2006 - 08/2002
1	Mycoplasma Pneumonia 01/2021
1	Hepatitis C 12/2017
1	Meningeal Tuberculosis (Tuberculous Meningitis) 12/2017
1	Pneumonia (Pneumonitis) 12/2017
1	Inflammation (Inflammations) 01/2012
1	Bacterial Infections (Bacterial Infection) 11/2006

Drug/Important Bio-Agent (IBA)

16	VaccinesIBA 12/2020 - 05/2003
9	AntigensIBA 12/2020 - 10/2005
9	Proteins (Proteins, Gene)FDA Link 12/2020 - 06/2005
5	Tuberculin (PPD)IBA 01/2016 - 05/2005
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 07/2014 - 12/2005
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2006 - 08/2002
3	PolyestersIBA 01/2016 - 03/2014
3	Tuberculosis VaccinesIBA 10/2013 - 01/2005
2	Subunit VaccinesIBA 12/2017 - 01/2017
2	BCG Vaccine FDA Link 01/2016 - 01/2014
2	Arginine (L-Arginine)FDA Link 07/2014 - 11/2007
2	Interleukin-10 (Interleukin 10)IBA 10/2012 - 11/2007
2	LipidsIBA 12/2011 - 05/2005
2	CytokinesIBA 09/2011 - 11/2006
2	Interferon-gamma (Interferon, gamma)IBA 11/2007 - 10/2005
2	A-Form DNA (A-DNA)IBA 07/2005 - 09/2003
1	Recombinases (Recombinase)IBA 01/2021
1	DNA (Deoxyribonucleic Acid)IBA 01/2021
1	Protein Subunit VaccinesIBA 12/2020
1	Biomarkers (Surrogate Marker)IBA 11/2018
1	MicroRNAs (MicroRNA)IBA 11/2018
1	polyhydroxybutyrateIBA 03/2014
1	poly(3-hydroxyalkanoic acid) synthaseIBA 12/2009
1	Interleukin-1beta (Interleukin 1 beta)IBA 08/2008
1	Vaccine AdjuvantsIBA 05/2008
1	Interleukin-2 (IL2)IBA 11/2007
1	tryptophan methyl esterIBA 11/2007
1	Immunologic Factors (Immunomodulators)IBA 11/2007
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 11/2007
1	Transforming Growth Factor beta (TGF-beta)IBA 11/2007
1	DioxygenasesIBA 11/2007
1	Neutralizing AntibodiesIBA 11/2007
1	NitritesIBA 11/2006
1	Interleukin-12 (IL 12)IBA 12/2005
1	CPG-oligonucleotideIBA 06/2005
1	OligodeoxyribonucleotidesIBA 06/2005
1	Protein Subunits (Protein Subunit)IBA 06/2005
1	Biological ProductsIBA 05/2003
1	Cholera ToxinIBA 08/2002

Therapy/Procedure

1	Oral Administration 05/2005